ihosäätöä

Ihosäätöä, or skin regulation, is a term used in dermatology and cosmetic science to describe processes that maintain the skin's barrier, hydration, lipid balance, immune readiness, and sensory responses. It encompasses how healthy skin preserves homeostasis and how these processes change in disease and with ageing.

The main mechanisms include the barrier function of the stratum corneum, control of transepidermal water loss and moisture, lipid synthesis (ceramides, fatty acids, cholesterol), keratinocyte turnover, and local immune signaling, as well as interactions with the skin microbiome and temperature-related blood flow.

Ihosäätöä is influenced by both intrinsic factors such as age, hormones, genetics, and health, and extrinsic factors such as climate, humidity, UV exposure, detergents, cosmetics, medications, and occupational exposure. Disruptions are common in conditions like atopic dermatitis, psoriasis, rosacea, and contact dermatitis.

Assessment uses noninvasive methods such as transepidermal water loss measurements, corneometry for hydration, sebummetry, and pH testing. Practically, products and therapies aim to support ihosäätöä with emollients, humectants, ceramides, anti-inflammatory agents, and protective formulations.

The concept guides research, product development, and clinical practice by highlighting how the skin restores balance under varying environments. Ongoing work seeks to clarify the links between the barrier, microbiome, and immune responses to improve regulation across populations.