hyalein

Hyalein is a protein found in the human body that plays a crucial role in the development and maintenance of various tissues. It belongs to the hyaluronan-binding protein family and is structurally related to aggrecan and versican. Hyalein's primary function is to bind to hyaluronan, a long, unbranched polysaccharide that is a major component of the extracellular matrix. This binding ability allows hyalein to contribute to the structural integrity and hydration of connective tissues, cartilage, and skin.

The gene encoding hyalein is located on chromosome 19. While its exact tissue distribution and specific roles are still under investigation, hyalein has been identified in several organs, including the lungs, kidneys, and eyes. Research suggests that hyalein may be involved in processes such as cell adhesion, cell migration, and wound healing. Its interaction with hyaluronan is thought to modulate the physical properties of the extracellular matrix, influencing cell behavior and tissue organization. Aberrant expression or function of hyalein has been implicated in certain pathological conditions, although more research is needed to fully understand these connections.