hematologieanalyzers

Hematologieanalyzers are automated instruments used to perform complete blood counts (CBC) and related hematology tests on peripheral blood samples. They provide rapid, standardized measurements that support diagnosis and treatment decisions in clinical laboratories.

Most analyzers use electrical impedance (the Coulter principle) or optical methods to count and size cells; many also employ fluorescence-based flow cytometry to improve differential counts. Modern systems may combine technologies to enhance accuracy and enable reticulocyte counting and other specialized parameters.

Typical outputs include red blood cell count, hemoglobin, hematocrit, and derived indices such as mean corpuscular volume, mean corpuscular hemoglobin, and mean corpuscular hemoglobin concentration, along with white blood cells (including a five-part differential), platelets, and metrics like mean platelet volume. Reticulocytes are reported on many platforms.

Hematologieanalyzers feature automated sample handling, dilution, and data processing, with regular calibration and onboard quality-control procedures. Pre-analytical factors such as sample age, clots, lipemia, and hemolysis can affect results and may necessitate repeat testing or confirmatory methods. Interference from abnormal cells or extreme counts may also require manual review.

Applications span hospital and clinical laboratories, with point-of-care devices offering smaller, rapid solutions for near-patient testing. Results are typically integrated with laboratory information systems to support reporting, trend analysis, and clinical decision making.