gonadotropinfrigivelse
Gonadotropinfrigivelse, or gonadotropin release, refers to the secretion of the anterior pituitary gonadotropins—luteinizing hormone (LH) and follicle-stimulating hormone (FSH)—in response to gonadotropin-releasing hormone (GnRH) from the hypothalamus. The process is essential for regulating gonadal function and gametogenesis in both sexes.
GnRH is released from hypothalamic neurons in pulsatile bursts and travels to the anterior pituitary via the
Feedback regulation involves sex steroids and gonadal peptides. Estrogen, testosterone, and progesterone provide negative feedback to
Clinically, impaired or dysregulated gonadotropinfrigivelse underlies conditions such as central (hypothalamic) precocious puberty, hypogonadotropic hypogonadism, and