glycomicsonderzoek
Glycomicsonderzoek, or glycomics research, is the scientific study of glycans, diverse carbohydrate structures that decorate proteins, lipids, and other molecules. The field seeks to catalog glycan structures, understand their biosynthesis, and determine their roles in biology. Glycans can be N-linked or O-linked on proteins, form glycosaminoglycans, or exist as glycolipids and free oligosaccharides. Their branching, linkage types, and stereochemistry strongly influence recognition, signaling, and cellular interactions.
Core methods combine release, derivatization, and identification of glycans with high-resolution separation and analysis. Mass spectrometry,
Glycomicsonderzoek informs biomedicine and biotechnology, including biomarker discovery for cancer and inflammatory diseases, study of congenital
Challenges include structural isomerism, sample preparation biases, and data integration across platforms. Standardization and reproducibility remain