glycerophosphoethanolamine
Glycerophospholipids are a major class of lipids that form the structural basis of cellular membranes in all domains of life. They consist of a glycerol backbone esterified at the first two positions with fatty acids and linked at the third position to a phosphate group that bears a polar head group. The combination of hydrophobic fatty acyl chains and a hydrophilic head group gives amphipathic molecules essential for membrane bilayer formation and curvature.
The most common head groups in eukaryotes are choline (phosphatidylcholine), ethanolamine (phosphatidylethanolamine), serine (phosphatidylserine), and inositol
Biosynthesis occurs via the glycerol-3-phosphate pathway. Glycerol-3-phosphate is acylated to form lysophosphatidic acid and then phosphatidic
Hydrolysis by phospholipases A, C, or D releases fatty acids, diacylglycerol, or head group-derived products, integrating