epitopspreading
Epitope spreading is a phenomenon observed in the immune system where the immune response shifts from targeting a single epitope on a pathogen to targeting multiple epitopes on the same pathogen. This shift occurs as the immune system adapts to the changing presentation of pathogens during infection or vaccination.
Epitope spreading is a result of the initial immune response targeting a single dominant epitope, typically
As the immune system is presented with these new epitopes, it may mount an immune response against
Epitope spreading is a complex and multi-factorial process that can influence both vaccine efficacy and pathogen