endotoksinina

Endotoxins are a component of the outer membrane of Gram-negative bacteria. They are lipopolysaccharides (LPS) and are released when the bacteria die and their cell walls break down. Endotoxins are not proteins and are generally heat-stable, meaning they are not destroyed by cooking. When endotoxins enter the bloodstream of a host, they can trigger a strong immune response, leading to a condition known as endotoxemia. This immune response can cause a variety of symptoms, including fever, inflammation, and a drop in blood pressure, which can be life-threatening if severe. The presence of endotoxins is a significant factor in the pathogenicity of many Gram-negative bacteria and is a concern in medical settings, particularly with the use of medical devices or contaminated solutions. Diagnostic tests exist to detect endotoxins, and methods are employed to remove them from pharmaceutical products to prevent adverse reactions.