egzónösszeállításokat

Exon assembly refers to the process of identifying and ordering the protein-coding regions of a gene, known as exons, within a larger DNA sequence. This is a crucial step in gene annotation and understanding gene structure. During transcription, the entire gene, including introns (non-coding regions), is copied into messenger RNA (mRNA). Subsequently, introns are spliced out, leaving only the exons, which are then translated into proteins.

The identification of exon assemblies is often facilitated by comparing mRNA sequences with genomic DNA sequences. Regions of the genomic DNA that match the mRNA sequence, with intervening introns, indicate the presence and order of exons. Computational tools and databases play a significant role in performing these comparisons and reconstructing the exon assembly. Understanding exon assemblies is vital for predicting protein structures, studying gene regulation, and identifying genetic variations that might affect protein function. It is a fundamental concept in molecular biology and bioinformatics.