dryblock

A dry block, also known as a dry bath or heat block, is a laboratory instrument used to heat or cool samples. It consists of a heating or cooling element and a block with precisely sized holes or wells designed to hold vials, tubes, or other sample containers. The block is typically made of a material that conducts heat well, such as aluminum.

The primary function of a dry block is to provide uniform and controlled temperature incubation for biological or chemical samples. Unlike water baths, which use water as the heat transfer medium, dry blocks utilize a solid metal block, eliminating the risk of contamination from waterborne microorganisms and preventing evaporation from samples. This makes them ideal for applications requiring sterile conditions or for heating sensitive samples.

Dry blocks are commonly used in molecular biology for applications such as PCR (polymerase chain reaction) reagent preparation, enzyme digestions, and DNA denaturation. They are also utilized in chemistry for sample preparation, incubation, and reactions requiring specific temperatures. The temperature of the dry block can be precisely set and maintained through an integrated thermostat, often with digital displays for accuracy. Many dry blocks also offer programmable ramp and soak functions, allowing for complex temperature profiles to be executed automatically. Their compact size and ease of use make them a versatile and essential piece of equipment in many research and diagnostic laboratories.