dithiolane
Dithiolane, specifically the 1,3-dithiolane isomer, is a five-membered heterocycle containing two sulfur atoms at positions 1 and 3. Its ring comprises three carbon atoms and two sulfur atoms, giving the formula C3H6S2. The structure is the saturated thioacetal derived from a carbonyl compound and the reagent ethane-1,2-dithiol.
In nomenclature, 1,3-dithiolane is distinguished from 1,3-dithiane, which is a six-membered ring (derived from 1,3-propanedithiol). Dithiolanes
Applications and properties: Dithiolanes are used as protecting groups for aldehydes and ketones. They form readily
Deprotection and related chemistry: Removal of the dithiolane protection typically proceeds by desulfurization to restore the
Safety and handling: Sulfur-containing reagents can be malodorous and toxic; proper ventilation and protective equipment are