deazaguanosinecontaining
Deazaguanosinecontaining refers to nucleosides or nucleic acids that incorporate a deazaguanosine moiety. Deazaguanosine is a modified guanosine analog where one or more nitrogen atoms in the purine ring are replaced by carbon atoms. Specifically, in the most common form, the nitrogen at position 7 is replaced by a carbon atom, resulting in 7-deazaguanosine. This structural alteration can significantly impact the base-pairing properties, metabolic fate, and biological activity of the resulting nucleoside or nucleic acid.
Incorporating deazaguanosine into DNA or RNA can lead to changes in their physical and chemical characteristics.
Research into deazaguanosine analogs has explored their potential as antiviral or anticancer agents. The altered structure