dNDPs
Deoxynucleotide diphosphates (dNDPs) are deoxyribonucleoside diphosphates, molecules consisting of a deoxyribonucleoside linked to two phosphate groups. They function as intermediates in the intracellular metabolism of deoxynucleotides and in the maintenance of the dNTP pool required for DNA replication and repair. The four base-specific dNDPs are dADP, dCDP, dGDP, and dTDP.
Formation and interconversion occur through phosphorylation and dephosphorylation reactions that connect the monophosphate, diphosphate, and triphosphate
Biological significance centers on the tight control of the dNTP pool. Adequate and balanced dNTP levels are