cyanokit
Cyanokit is a brand-name antidote for cyanide poisoning that contains hydroxocobalamin, a form of vitamin B12, prepared for intravenous administration. It is used in emergencies to treat cyanide poisoning resulting from smoke inhalation, chemical exposure, or other sources of cyanide.
Mechanism of action: hydroxocobalamin binds cyanide ions to form cyanocobalamin, a non-toxic compound that is renally
Administration and dosing: Cyanokit is given by intravenous infusion. The typical adult dose is 5 grams administered
Contraindications and cautions: contraindicated in patients with known hypersensitivity to hydroxocobalamin or cobalt. The solution can
Adverse effects: flushing, hypertension or hypotension, tachycardia, nausea, vomiting, headache; transient chromaturia (reddish discoloration of urine)
Regulatory status: Cyanokit has been approved for the treatment of cyanide poisoning in adults and children