cholecystokininas

Cholecystokinin, often abbreviated as CCK, is a peptide hormone produced by cells in the lining of the small intestine, specifically the duodenum and jejunum. It is also found in the brain, where it functions as a neurotransmitter. CCK plays a crucial role in digestion and satiety.

In the digestive system, CCK is released in response to the presence of fats and proteins in the duodenum. Its primary functions include stimulating the gallbladder to contract and release bile, which aids in the digestion and absorption of fats. CCK also promotes the secretion of pancreatic enzymes from the pancreas, further assisting in the breakdown of food. It slows down the rate at which the stomach empties its contents into the small intestine, allowing more time for digestion.

In the brain, CCK acts as a neuromodulator and is involved in various physiological processes. It has been implicated in feelings of fullness and satiety, contributing to the regulation of appetite and food intake. CCK also plays a role in pain perception, anxiety, and memory. The release of CCK is regulated by the digestive contents of the small intestine, and its actions are mediated through specific CCK receptors located throughout the body and brain.