chelidonine

Chelidonine is an alkaloid found in the greater celandine plant (Chelidonium majus). It belongs to the isoquinoline alkaloid class. While the plant has a long history of traditional medicinal use, scientific research into the specific effects and properties of chelidonine is ongoing. Studies have explored its potential pharmacological activities, including anti-inflammatory, analgesic, and antispasmodic properties in vitro and in animal models. However, much of this research is preliminary and requires further investigation to establish efficacy and safety in humans.

The chemical structure of chelidonine is characterized by a benzo[c]phenanthridine skeleton. It is one of several alkaloids present in Chelidonium majus, with sanguinarine and protopine also being significant components. The concentration of chelidonine can vary depending on the plant's origin, harvest time, and extraction methods. Due to its presence in a plant with historical uses for skin conditions and digestive issues, chelidonine has been a subject of interest for natural product chemists and pharmacologists. However, it is important to note that the medicinal use of plants containing chelidonine is not without risks, and self-medication is not recommended. Further clinical trials are needed to validate any potential therapeutic benefits and to understand its toxicological profile.