celltypewise
celltypewise is a computational approach used in biological research, particularly in the analysis of single-cell RNA sequencing (scRNA-seq) data. The core principle of celltypewise analysis is to examine biological features, such as gene expression patterns or regulatory elements, on a per-cell-type basis. Instead of analyzing the entire population of cells collectively, celltypewise methods disaggregate the data by identified cell types. This allows researchers to pinpoint cell type-specific responses, functions, or molecular characteristics that might be obscured in a bulk analysis.
This approach is crucial because different cell types within a tissue or sample often exhibit distinct molecular