calixarened
Calixarened is an adjective used in chemistry to describe molecules or materials that incorporate calix[ n ]arene units into their structure. Calix[ n ]arenes are a family of macrocyclic compounds composed of phenol rings linked by methylene bridges, forming cup-shaped cavities that can host various guest species. When a molecule is described as calixarened, its architecture features at least one calixarene moiety, typically calix[4]arene, appended to a core framework or linked to other functional units. The calixarene unit provides a preorganized binding site and can impart selective recognition and encapsulation properties.
Synthesis and functionalization: Calixarenes are generally prepared by condensation of phenol derivatives with formaldehyde under basic
Applications and relevance: Calixarened materials are explored for host–guest chemistry, ion transport, catalysis, sensing, separations, and
See also: calixarenes, macrocyclic compounds, host-guest chemistry, supramolecular chemistry.