cVDPV
Circulating vaccine-derived poliovirus (cVDPV) is a poliovirus that originated from the attenuated virus used in the oral polio vaccine (OPV) and has mutated to regain properties that allow it to spread in a population. VDPVs are categorized as circulating when they evidence sustained person-to-person transmission in communities, typically causing outbreaks similar to those caused by wild poliovirus.
cVDPV arises when vaccine-derived strains circulate in populations with low vaccination coverage and poor sanitation. As
There are three genetic types of cVDPV: cVDPV1, cVDPV2, and cVDPV3, corresponding to the Sabin type they
Control and prevention focus on rapid outbreak response and increasing population immunity. This includes strengthening routine