cMDH
cMDH stands for conformational Multi-Domain Hydrophobicity, a concept in molecular and structural biology that describes the dynamic behavior of proteins and other biomolecules based on their hydrophobicity profiles across multiple domains. This concept emphasizes the importance of conformational flexibility in biological functions, such as enzymatic activity, molecular recognition, and signal transduction.
The core principle of cMDH involves the spatial distribution of hydrophobic and hydrophilic regions within a
Research on cMDH integrates computational modeling, such as molecular dynamics simulations, with experimental techniques like nuclear
Applications of cMDH are notable in drug design and development, where understanding the conformational variability of
Overall, cMDH provides a framework for studying the dynamic nature of biomolecules, emphasizing how conformational changes