blaKPC4carrying
blaKPC4carrying refers to the presence of the blaKPC-4 gene within a bacterial organism. This gene encodes for a carbapenemase, specifically a Klebsiella pneumoniae carbapenemase (KPC) of the KPC-4 variant. Carbapenemases are enzymes that can hydrolyze and inactivate carbapenem antibiotics, which are often considered last-resort treatments for multidrug-resistant bacterial infections. Therefore, bacteria carrying the blaKPC-4 gene are typically resistant to a broad range of beta-lactam antibiotics, including carbapenems.
The blaKPC-4 gene is commonly found on mobile genetic elements such as plasmids, which can be transferred