bindinginduced
Bindinginduced refers to phenomena in which the binding of a ligand or partner to a biomolecule triggers structural rearrangements, changes in dynamics, or assembly into higher-order complexes, producing a functional response. The concept is central to understanding signaling, catalysis, and gene regulation, and is used across biochemistry, biophysics, and structural biology.
Mechanisms include allosteric effects, where binding at one site influences distant sites; induced fit, where binding
In proteins, bindinginduced changes can activate enzymes, propagate signals through receptors such as G protein–coupled receptors
Studying bindinginduced processes relies on biophysical and structural techniques. Isothermal titration calorimetry and other calorimetry methods