betaMSH

betaMSH, also known as beta-melanocyte-stimulating hormone, is a peptide hormone that plays a role in pigmentation in mammals. It is a fragment of the larger proopiomelanocortin (POMC) molecule, which is produced in the pituitary gland. BetaMSH is specifically generated through the enzymatic cleavage of POMC. Its primary function is to stimulate melanocytes, the cells responsible for producing melanin, the pigment that gives color to skin, hair, and eyes. In many species, betaMSH contributes to tanning and the darkening of skin in response to sunlight.

The release of betaMSH is regulated by various factors, including light exposure and hormonal signals. While its role in pigmentation is well-established, research has also suggested potential involvement in other physiological processes. These have included effects on appetite, sexual behavior, and inflammation, although these functions are generally less pronounced or understood compared to its melanogenic effects. The concentration of betaMSH can vary depending on species and physiological state. Its interaction with melanocortin receptors is key to its biological activity.