azidotransfertype
Azidotransfertype is a term used in a limited portion of biochemistry and chemical biology literature to denote a class of reactions and enzymes that mediate the transfer of azide groups (−N3) from a donor molecule to an acceptor substrate, producing an azido-functionalized product. The term is not part of the formal IUBMB enzyme nomenclature and is not universally standardized; in many sources the concept is described using more specific labels such as azidotransferase or azide-transfer reactions rather than as a single, well-defined type.
Mechanistically, azide transfer can involve activation of the azide donor and transfer through a catalytic intermediate,
Substrates and donors vary widely; donors include azido-activated cofactors or small molecules, and acceptors can be
Applications of azidotransfertype concepts include enabling site-specific labeling for imaging, proteomics, and targeted drug delivery through