antiangiogén

Antiangiogenesis is a biological process that inhibits the formation of new blood vessels, a phenomenon known as angiogenesis. Blood vessel formation is crucial for various physiological processes, including growth, development, and wound healing. However, it also plays a significant role in pathological conditions, particularly in the growth and spread of tumors.

Tumors require a continuous supply of oxygen and nutrients to grow beyond a certain size and to metastasize to distant sites. They achieve this by stimulating the formation of new blood vessels from pre-existing ones, a process driven by the release of specific growth factors. Antiangiogenic therapies aim to disrupt this process by blocking these signals or targeting the endothelial cells that form the new blood vessels.

The development of antiangiogenic drugs represents a significant advancement in cancer treatment. These therapies can be used alone or in combination with other treatments like chemotherapy or radiation therapy. By limiting the tumor's blood supply, antiangiogenic agents can slow down tumor growth, reduce metastasis, and in some cases, even lead to tumor shrinkage. However, like all treatments, antiangiogenic therapies can have side effects, which vary depending on the specific drug used. Research continues to explore new and more effective antiangiogenic strategies for various diseases.