alpha2Cselective
alpha2Cselective is a term used in pharmacology to describe compounds that exhibit a high affinity for and preferentially bind to the alpha-2C adrenergic receptor subtype. Adrenergic receptors are a class of G protein-coupled receptors that are activated by the catecholamines, norepinephrine and epinephrine. There are several subtypes of adrenergic receptors, including alpha-1, alpha-2, beta-1, beta-2, and beta-3. The alpha-2 receptors are further divided into alpha-2A, alpha-2B, and alpha-2C subtypes.
Compounds that are alpha2Cselective are designed to target the alpha-2C receptor with minimal interaction with the
The alpha-2C adrenergic receptor is found in various tissues, including the brain, spinal cord, and peripheral