adenosinerelated
Adenosine-related refers to processes, molecules, and pathways centered on the nucleoside adenosine and its derivatives. Adenosine is a purine nucleoside composed of adenine attached to ribose. It plays roles as a building block of energy carriers and as a signaling molecule that coordinates cellular responses to energy status, stress, and inflammation.
Biochemical origin and metabolism: Adenosine is produced intracellularly from AMP and can be generated extracellularly by
Adenosine acts mainly through four G protein–coupled receptors: A1, A2A, A2B, and A3. A1 and A3 generally
Clinical uses and pharmacology: Adenosine itself is used acutely to terminate certain supraventricular tachycardias due to
Research and broader relevance: The adenosine pathway is implicated in tumor immunology and inflammatory disease, where