adenomatosis

Adenomatosis is a general term used in medicine to describe the abnormal proliferation of glandular tissue. This proliferation can occur in various organs and tissues, and its specific characteristics and implications depend on the location and nature of the glandular tissue involved. It is not a single disease but rather a descriptive term for a cellular change.

In some contexts, adenomatosis refers to a condition where numerous adenomas, which are benign tumors arising from glandular epithelial cells, are present. The number and distribution of these adenomas can vary significantly. For example, multiple endocrine adenomatosis syndromes involve the development of tumors in several endocrine glands.

Another manifestation is diffuse adenomatosis, where there is a widespread increase in glandular tissue, often without forming discrete nodules. This can lead to organ enlargement or functional changes. The term can also be used to describe specific conditions like mammary duct ectasia, which can sometimes be referred to as periductal adenomatosis in its more severe forms, characterized by dilation and inflammation of the milk ducts often accompanied by cellular changes.

The diagnosis and management of adenomatosis are dependent on the affected organ and the specific type of glandular proliferation. This may involve imaging studies, biopsies, and appropriate medical or surgical interventions to address the underlying cause and manage any associated symptoms or risks.