Zielorganell

Zielorganell is a German term that translates to "target organelle" in English. It refers to a specific organelle within a cell that is the intended recipient of a molecule, such as a drug, toxin, or signaling molecule. This target organelle is chosen because it plays a crucial role in a particular cellular process that is being influenced or modified.

The concept of a target organelle is particularly relevant in pharmacology and toxicology. When a drug is administered, its efficacy often depends on its ability to reach and interact with a specific organelle within the target cells. For example, some chemotherapy drugs work by targeting organelles involved in cell division, such as the nucleus or mitochondria. Similarly, toxins can exert their harmful effects by disrupting the function of specific organelles.

Identifying the target organelle is a critical step in understanding how a particular substance exerts its effects at the cellular level. It helps researchers to design more effective drugs with fewer side effects by ensuring that the active compound is delivered to the correct location within the cell. Conversely, understanding target organelles is also vital for developing antidotes or strategies to mitigate the effects of toxic substances. Research into target organelles contributes to our broader understanding of cellular biology and the complex mechanisms that govern life.