Valmate

Valmate is a brand name for a medication containing the active ingredient fluphenazine decanoate. Fluphenazine decanoate is a long-acting injectable antipsychotic medication belonging to the phenothiazine class. It is primarily used for the management of schizophrenia and other psychotic disorders. The decanoate ester formulation allows for slow release of the drug into the bloodstream over a period of several weeks, typically two to four weeks, reducing the need for daily oral medication. This depot injection is administered intramuscularly.

The mechanism of action for fluphenazine decanoate involves blocking dopamine receptors in the brain, which is believed to help reduce the positive symptoms of psychosis, such as hallucinations and delusions. It may also have some effect on negative symptoms. Valmate is generally prescribed by psychiatrists and administered by healthcare professionals. Dosage and frequency of administration are determined based on individual patient needs and response. Like other antipsychotics, Valmate can cause side effects, which may include drowsiness, dry mouth, blurred vision, and movement disorders such as tardive dyskinesia. Close monitoring by a healthcare provider is essential to manage potential side effects and assess treatment effectiveness. It is not typically used for acute agitation or as a first-line treatment for all psychotic conditions.