Tyr505

Tyr505 is a specific residue, the amino acid tyrosine, located at position 505 within a protein sequence. The "Tyr" denotes the amino acid tyrosine, and "505" indicates its position in the linear chain of amino acids that make up the protein. Tyrosine is an aromatic amino acid containing a hydroxyl group, which can participate in various chemical reactions, including phosphorylation.

The significance of Tyr505 often lies in its role as a regulatory site. Phosphorylation, the addition of a phosphate group to the hydroxyl group of tyrosine, is a common post-translational modification that can alter a protein's activity, stability, or interactions with other molecules. In many signaling pathways, specific tyrosine residues act as docking sites for other proteins or as activation/inactivation switches for the protein they reside in.

Research into a particular protein will often highlight the importance of its Tyr505 residue. Studies might investigate whether this tyrosine is phosphorylated under certain conditions, what enzymes are responsible for its phosphorylation or dephosphorylation, and what downstream effects these modifications have on cellular processes. Therefore, Tyr505 is not a standalone entity but rather a functional component within a larger protein context, critical for understanding the protein's biological function and regulation.