TubercuList

TubercuList is an online genome database dedicated to the annotations of the Mycobacterium tuberculosis H37Rv reference genome. It serves as a centralized resource for researchers by providing gene-centric information that summarizes the current understanding of individual genes and their products.

Each gene page in TubercuList typically includes the locus tag (Rv number), standard gene name and synonyms, predicted or assigned function, the encoded protein product, and the gene’s genomic coordinates. Entries also offer links to related data and literature, and where available may include notes on experimental evidence, predicted protein domains, and functional context such as involvement in pathways or cellular processes. In addition, the database often presents information about gene operons, potential essentiality, and comparative notes with related strains or species.

Users can search TubercuList by gene name, locus tag, function, or genomic location, and can browse groups of genes within operons or genomic regions. The interface is designed to support data retrieval for experimentation, hypothesis generation, and literature discovery. Data and annotations are regularly updated to reflect new experimental results and revised genome annotations, with TubercuList functioning as a living reference alongside primary sequence databases.

Maintenance of TubercuList is the result of collaborative efforts among tuberculosis researchers and sequencing centers, aiming to provide stable, citable gene information that supports TB research and education. The resource is widely used for planning experiments, annotating findings, and cross-referencing genomic data within the tuberculosis research community.