H37Rv
H37Rv is a virulent laboratory strain of Mycobacterium tuberculosis that has served as a standard reference strain in tuberculosis research for decades. It is derived from the H37 lineage, with H37Rv representing the virulent derivative, while a closely related variant called H37Ra is the attenuated, avirulent form used in some vaccine studies. The designation H37Rv has become a canonical reference in many laboratories for phenotypic and molecular studies of the tuberculosis bacterium.
Genome and characteristics: The complete genome of H37Rv was published in 1998 and has since served as
Research applications and containment: H37Rv is widely used in drug susceptibility testing, vaccine research, pathogenesis studies,
Availability: The strain is distributed by major culture collections and research institutions under proper biosafety provisions,