Toksikokineetikaks

Toksikokineetikaks refers to the study of how toxic substances move into, through, and out of the body over time. It encompasses the processes of absorption, distribution, metabolism, and excretion (ADME) as they relate to poisons and other harmful chemicals. Understanding toxicokinetics is crucial for assessing the potential health risks associated with exposure to a toxicant. Absorption describes how a substance enters the body, whether through ingestion, inhalation, or dermal contact. Distribution details how the substance spreads throughout the body's tissues and organs. Metabolism, also known as biotransformation, involves the chemical alteration of the toxicant by the body, which can either detoxify it or sometimes create more harmful substances. Finally, excretion is the process by which the body eliminates the toxicant and its metabolites, typically through urine, feces, breath, or sweat. The rate and extent of these processes determine the concentration of the toxicant in various tissues and its duration of action, influencing the severity and type of toxic effects observed. Toxicokinetic data is essential for setting exposure limits, developing biomonitoring strategies, and designing effective treatments for poisoning.