Tobramicina

Tobramicina is an aminoglycoside antibiotic used to treat a variety of bacterial infections. It is effective against many Gram-negative bacteria, including Pseudomonas aeruginosa, and some Gram-positive bacteria. Tobramicina works by inhibiting bacterial protein synthesis, which ultimately leads to bacterial cell death.

Tobramicina is available in several formulations, including intravenous (IV), intramuscular (IM), inhaled, and ophthalmic (eye drops). The route of administration and dosage depend on the type and severity of the infection, as well as the patient's age and kidney function. For systemic infections, it is typically administered intravenously or intramuscularly. Inhaled tobramicina is used for the management of chronic lung infections in patients with cystic fibrosis. Ophthalmic preparations are used to treat bacterial eye infections.

Common side effects of tobramicina can include kidney problems (nephrotoxicity) and hearing loss (ototoxicity). These risks are generally dose-dependent and can be minimized by careful monitoring of drug levels and kidney function. Other potential side effects include nausea, vomiting, and rash. Tobramicina is generally not recommended for pregnant or breastfeeding women due to potential risks to the fetus or infant. It is crucial for healthcare providers to weigh the benefits against the risks when prescribing tobramicina.