Thr58

Thr58 is a specific amino acid residue found within certain protein structures. Amino acids are the building blocks of proteins, and their specific positions within a protein chain play a crucial role in the protein's overall function and three-dimensional shape. The designation "Thr58" indicates that the amino acid at position 58 in the protein sequence is threonine (Thr). Threonine is one of the twenty standard amino acids and is characterized by its polar side chain containing a hydroxyl group. This hydroxyl group can participate in hydrogen bonding and other interactions that are important for protein folding and the binding of other molecules. The precise biological significance of Thr58 depends entirely on the specific protein in which it is located. Its presence or absence, or mutations at this position, can have profound effects on protein stability, enzymatic activity, or interactions with other cellular components. Researchers often study specific amino acid residues like Thr58 to understand disease mechanisms or to design targeted therapies by altering protein function. Information about Thr58 would typically be found in databases of protein sequences and structures, such as the Protein Data Bank (PDB) or UniProt.