Thomsonin
Thomsonin is a synthetic organic compound of interest in coordination chemistry and medicinal chemistry. The compound is named after the Thomson Institute for Molecular Science, where it was first described in early studies of heterocyclic ligands. Thomsonin is classified as a polyfunctional heterocycle featuring a fused bicyclic core with a pendant arylidene substituent and a thioether side chain. The molecule exists predominantly as a racemate in standard solvent systems, with isomerization possible under photochemical conditions.
Synthesis and structure: Thomsonin is typically prepared by a two-step sequence starting from a 1,3-dicarbonyl precursor
Properties: Thomsonin is a white to off-white solid with moderate stability under ambient light and heat. It
Applications: In research, Thomsonin serves as a ligand scaffold for metal-catalyzed reactions and as a lead
Safety: Information on toxicity is limited to preliminary screening. It should be handled with standard laboratory