Thiodiglycolic

Thiodiglycolic acid, also known as thiodiacetic acid or simply thiodiglycolic, is an organic compound with the chemical formula S(CH2COOH)2. It is a dicarboxylic acid where the two carboxyl groups are linked by a sulfur atom. This sulfur atom is in the +2 oxidation state. Thiodiglycolic acid is a white crystalline solid and is soluble in water and polar organic solvents.

The compound can be synthesized through several methods, including the reaction of sodium sulfide with chloroacetic acid or the hydrolysis of thiodiglycolic acid esters. Thiodiglycolic acid is primarily used as a chemical intermediate. Its derivatives find applications in various fields. For instance, it can be used in the synthesis of polymers, pharmaceuticals, and agricultural chemicals. It has also been investigated for its antioxidant properties and as a chelating agent due to the presence of the sulfur atom and carboxyl groups. In some analytical chemistry procedures, it has been employed as a reagent. The toxicity profile of thiodiglycolic acid is generally considered moderate, but specific handling precautions are advised.