Tepronomin

Tepronomin is a hypothetical organic compound used in pharmacology pedagogy to illustrate concepts in neurotransmission and receptor pharmacology. It is not a defined chemical entity in the peer-reviewed literature and has no approved medical use.

Chemical identity. In fictional descriptions, tepronomin is a small, lipophilic amide with a bicyclic core. The proposed molecular formula is C14H18N2O3, with an estimated molecular weight of about 254 g/mol and a logP near 2.7, features that would suggest brain penetration in models.

Pharmacology. In theoretical models, tepronomin binds to a proposed class of pronomin receptors, a fictional family of G protein–coupled receptors. It is described as a partial agonist with moderate affinity, capable of modulating cAMP signaling and presynaptic neurotransmitter release. No empirical data support its activity in real systems.

Synthesis. In educational texts, tepronomin is prepared by a two-step sequence starting from a substituted aniline and an acylating agent, followed by cyclization to form the bicyclic core. No experimental procedures exist in the scientific literature.

History. The name tepronomin was introduced in 2023 in a teaching article to illustrate pharmacokinetic concepts such as absorption, distribution, and receptor occupancy. It is widely treated as a placeholder name rather than a real compound.

See also. Neuropharmacology, receptor pharmacology, placeholder names.