TPMTtestiä
TPMTtestiä is a Finnish term that translates to "TPMT testing" in English. TPMT refers to the enzyme thiopurine S-methyltransferase. This enzyme plays a crucial role in the metabolism of certain medications, particularly thiopurine drugs like azathioprine, mercaptopurine, and thioguanine. These drugs are commonly used in the treatment of autoimmune diseases, inflammatory conditions, and certain types of cancer.
TPMTtestiä is a pharmacogenetic test that determines an individual's activity level of the TPMT enzyme. Genetic
For individuals with low TPMT activity, thiopurine drugs can accumulate to toxic levels in the body, leading
Therefore, TPMTtestiä is often performed before initiating treatment with thiopurine medications. The results of the test