Supozime

Supozime is a term used in several languages to refer to a suppository, a solid dosage form designed for insertion into body cavities such as the rectum, vagina, or urethra. Suppositories are intended to melt or dissolve at body temperature, releasing the active drug for local or systemic effects.

Most suppositories consist of a drug mixed with a non-dissolving vehicle or base. Common bases include cocoa butter (theobroma oil), glycerinated gelatin, and various polyethylene glycols. Suppositories can be prepared by molding or by compression, and may be scored or coated to control release or handling.

Administrators insert suppositories into the appropriate cavity using a clean technique and may be advised to retain them for a period to ensure absorption. Suppositories are used for a range of purposes, including laxative effects for constipation, local treatment of hemorrhoids or infections, antiemetic or analgesic delivery when oral administration is not feasible, or fever reduction in certain patients.

Advantages of suppositories include bypassing the stomach and first-pass metabolism, usefulness when vomiting or swallowing is difficult, and the ability to target local symptoms. Limitations include variable absorption, potential for local irritation, and slower onset compared with some injectables.

Safety and handling considerations include proper storage at recommended temperatures, checking expiration dates, and avoiding use in individuals with known allergies to components. Suppositories are regulated pharmaceutical products, available in prescription and over-the-counter forms, depending on active ingredients and regional regulations. Some languages use supozime as the standard term for this dosage form.