Sortilinrelated
Sortilinrelated is a term that refers to proteins that share structural or functional similarities with sortilin. Sortilin itself is a transmembrane receptor protein that plays a crucial role in intracellular protein trafficking and sorting. It is a member of the vacuolar protein sorting (VPS) 10 domain family. Proteins related to sortilin often possess a VPS 10 domain, which is a characteristic feature responsible for binding and transporting various cargo molecules. These cargo molecules can include neurotrophins, hormones, enzymes, and other secreted or transmembrane proteins.
The function of sortilin-related proteins is diverse and often context-dependent. They are implicated in a wide