The underlying cause of sorbitoliintoleranssi is often related to a deficiency in the enzyme aldose reductase, which is responsible for converting sorbitol into fructose. This enzyme is found in the lens of the eye and is also present in other tissues, including the gastrointestinal tract. In individuals with sorbitoliintoleranssi, the activity of aldose reductase is reduced or absent, leading to an accumulation of sorbitol in the body and subsequent symptoms.
The diagnosis of sorbitoliintoleranssi typically involves a combination of clinical evaluation and laboratory testing. Symptoms are often triggered by the consumption of foods or beverages containing sorbitol, and a history of these symptoms can be an important clue to the diagnosis. Laboratory testing may include measurements of blood sugar levels, urine analysis, and genetic testing to identify mutations in the aldose reductase gene.
Treatment for sorbitoliintoleranssi focuses on avoiding foods and beverages that contain sorbitol. This may involve reading food labels carefully and choosing products that are labeled as sorbitol-free. In some cases, dietary supplements containing aldose reductase inhibitors may be prescribed to help manage symptoms. Additionally, maintaining proper hydration and avoiding excessive consumption of sugary foods can help alleviate symptoms and prevent dehydration.
In summary, sorbitoliintoleranssi is a condition characterized by the body's inability to metabolize sorbitol, leading to symptoms such as abdominal pain, bloating, and diarrhea. The underlying cause is often related to a deficiency in the enzyme aldose reductase. Diagnosis involves a combination of clinical evaluation and laboratory testing, and treatment focuses on avoiding sorbitol-containing foods and maintaining proper hydration.