Sihtmärgidest

Sihtmärgidest, also known as target organs, are specific organs or tissues in the body that are particularly susceptible to the toxic effects of certain substances. These substances can be drugs, chemicals, or other environmental agents. The concept of target organs is crucial in toxicology, as it helps in understanding the potential health risks associated with exposure to these agents.

The susceptibility of an organ to become a target organ can be influenced by several factors, including the chemical properties of the substance, the route of exposure, the duration and intensity of exposure, and individual factors such as age, sex, and overall health. For instance, the liver is often considered a target organ for many drugs and chemicals due to its role in metabolizing and detoxifying substances.

The effects on target organs can range from mild to severe, and may include damage to tissues, organ failure, or even death. In some cases, the effects may not be immediately apparent, leading to chronic health issues that develop over time. Therefore, identifying and understanding target organs is essential for developing effective strategies to prevent and mitigate the adverse effects of toxic substances.