Santísimo
Santísimo is a Spanish adjective meaning "most holy," used as an honorific in religious contexts to designate things regarded as sacred or consecrated. In Catholic and other Christian traditions, it appears in phrases that name the most sacred mysteries, figures, or devotions. The form is commonly paired with feminine or masculine nouns, such as Santísima Trinidad (Most Holy Trinity), Santísimo Sacramento (Most Holy Sacrament, referring to the Eucharist), and Santísimo Nombre de Jesús (Most Holy Name of Jesus).
Etymology and usage: Santísimo derives from Latin sanctissimus, a superlative of sanctus meaning holy or sacred.
In religious practice: The expression appears in titles and invocations across Spanish-speaking Catholic communities. Santísimo Sacramento
Other contexts: Beyond liturgy, Santísimo can appear in the naming of churches, confraternities, or devotional practices
See also: Most Holy Trinity, Blessed Sacrament, devotion to the Holy Name of Jesus.