STK11AMPK
STK11AMPK, also known as Senataxin and AMP-activated protein kinase subunit gamma 1, is a protein that plays a crucial role in various cellular processes. It is a serine-threonine kinase that is activated in response to various stresses, including exercise and caloric restriction. The enzyme is also a key regulator of the AMP-activated protein kinase (AMPK) pathway, which is involved in energy homeostasis and glucose and lipid metabolism.
STK11, an upstream regulatory subunit, is a tumor suppressor gene that is mutated in certain forms of
The AMPK pathway is involved in the regulation of metabolism, energy production, and cell growth. During exercise
Studies have also linked STK11/AMPK to the regulation of autophagy, a process in which cells recycle damaged