SNPchip

SNPchip, also known as a SNP array or SNP microarray, is a type of DNA microarray that is used to genotype single nucleotide polymorphisms (SNPs). SNPs are the most common type of genetic variation among people, and they can play a role in disease susceptibility, drug response, and other traits. SNPchips contain thousands or even millions of probes that are designed to bind to specific SNP alleles. DNA from a sample is labeled and hybridized to the chip, and the intensity of the signal at each probe location indicates which SNP alleles are present in the sample. This allows for the simultaneous genotyping of a large number of SNPs across the genome. SNPchips have been widely used in genetic research, including genome-wide association studies (GWAS) to identify genetic variants associated with diseases, as well as in population genetics and pharmacogenomics. The technology has evolved to offer higher density arrays and improved accuracy, making it a powerful tool for understanding genetic variation and its implications.