SFARI

SFARI, which stands for Simons Foundation Autism Research Initiative, is a major research program dedicated to understanding the causes and mechanisms of autism spectrum disorder (ASD) and developing better interventions. Established by Jim Simons and Marilyn Simons, the foundation aims to accelerate progress in autism research by supporting a wide range of scientific studies.

SFARI's work encompasses various research areas, including genetics, neuroscience, and behavioral studies. The initiative funds research into the genetic underpinnings of autism, seeking to identify genes and genetic variations associated with the condition. It also supports research into the brain, exploring neural circuits, connectivity, and the biological processes that may differ in individuals with autism.

A significant aspect of SFARI's mission is to facilitate data sharing and collaboration among researchers worldwide. They have developed and continue to support large-scale datasets, such as the Simons Simplex Collection (SSC) and the Simons Foundation Powering Autism Research for Knowledge (SPARK) database. These collections provide researchers with valuable genetic and phenotypic information from thousands of individuals with autism and their families, enabling more robust and comprehensive analyses.

SFARI also plays a role in fostering the development of novel therapeutic and diagnostic tools. By supporting innovative research and encouraging interdisciplinary approaches, the initiative strives to translate scientific discoveries into meaningful improvements in the lives of individuals with autism and their families. Their funding extends to a variety of research methodologies, from basic science investigations to clinical trials.