Rezeptorgekoppelte
Rezeptorgekoppelte, also known as G protein-coupled receptors (GPCRs), are a large family of cell surface receptors that play a crucial role in signal transduction. When an extracellular signaling molecule, such as a hormone or neurotransmitter, binds to a GPCR, it triggers a conformational change in the receptor. This change then activates an associated intracellular G protein.
The activated G protein, which is a heterotrimer consisting of alpha, beta, and gamma subunits, then dissociates.
The activation of these effector proteins leads to a cascade of intracellular events, ultimately resulting in