RNApohjaisilla

RNApohjaisilla is the Finnish term for retroviruses, a type of virus that is transmitted from a host through infectious particles known as virions. This group of viruses is composed of a single-stranded RNA genome. They are complex particles because they contain both genetic instructions (the genome) and enzymes required for replication. The viruses cannot replicate on their own, but require using the host cell's replication machinery.

Retroviruses are also characterized by their ability to integrate their genetic material into the host genome, allowing them to become a part of the host's DNA. This process is facilitated by an enzyme called integrase, which acts as a cornerstone for integration and unification of viral and host genetic material. Integration can lead to the production of ongoing viral infections and in the case of retroviruses, this can be lifelong.

Some notable types of RNApohjaisilla include lentiviruses, such as HIV, which causes AIDS, and HTLV-1, which is associated with some leukemias. Other retroviruses like the Friend virus can induce cancer-like symptoms in lab animals.

Currently, much of the ongoing research in this field is focused on creating vaccines for acute and long-term effects. Specific retroviruses have been shown to affect not just humans but other mammals as well. Proper understanding is especially important for the fields of medicine, especially oncology, which can aid in development of targeted therapy.